diff --git a/sanic/router.py b/sanic/router.py
index bd74c11d..052ff1bf 100644
--- a/sanic/router.py
+++ b/sanic/router.py
@@ -234,11 +234,11 @@ class Router:
             if properties['unhashable']:
                 routes_to_check = self.routes_always_check
                 ndx, route = self.check_dynamic_route_exists(
-                    pattern, routes_to_check)
+                    pattern, routes_to_check, parameters)
             else:
                 routes_to_check = self.routes_dynamic[url_hash(uri)]
                 ndx, route = self.check_dynamic_route_exists(
-                    pattern, routes_to_check)
+                    pattern, routes_to_check, parameters)
             if ndx != -1:
                 # Pop the ndx of the route, no dups of the same route
                 routes_to_check.pop(ndx)
@@ -285,9 +285,9 @@ class Router:
             self.routes_static[uri] = route
 
     @staticmethod
-    def check_dynamic_route_exists(pattern, routes_to_check):
+    def check_dynamic_route_exists(pattern, routes_to_check, parameters):
         for ndx, route in enumerate(routes_to_check):
-            if route.pattern == pattern:
+            if route.pattern == pattern and route.parameters == parameters:
                 return ndx, route
         else:
             return -1, None
diff --git a/tests/test_routes.py b/tests/test_routes.py
index 84d6b221..5f3b3376 100644
--- a/tests/test_routes.py
+++ b/tests/test_routes.py
@@ -2,7 +2,7 @@ import asyncio
 import pytest
 
 from sanic import Sanic
-from sanic.response import text
+from sanic.response import text, json
 from sanic.router import RouteExists, RouteDoesNotExist
 from sanic.constants import HTTP_METHODS
 
@@ -907,3 +907,27 @@ def test_unicode_routes():
 
     request, response = app.test_client.get('/overload/你好')
     assert response.text == 'OK2 你好'
+
+
+def test_uri_with_different_method_and_different_params():
+    app = Sanic('test_uri')
+
+    @app.route('/ads/<ad_id>', methods=['GET'])
+    async def ad_get(request, ad_id):
+        return json({'ad_id': ad_id})
+
+    @app.route('/ads/<action>', methods=['POST'])
+    async def ad_post(request, action):
+        return json({'action': action})
+
+    request, response = app.test_client.get('/ads/1234')
+    assert response.status == 200
+    assert response.json == {
+        'ad_id': '1234'
+    }
+
+    request, response = app.test_client.post('/ads/post')
+    assert response.status == 200
+    assert response.json == {
+        'action': 'post'
+    }