diff --git a/sanic/response.py b/sanic/response.py
index 09c92225..7b245a82 100644
--- a/sanic/response.py
+++ b/sanic/response.py
@@ -1,3 +1,4 @@
+from functools import partial
 from mimetypes import guess_type
 from os import path
 from urllib.parse import quote_plus
@@ -12,7 +13,11 @@ from sanic.helpers import STATUS_CODES, has_message_body, remove_entity_headers
 try:
     from ujson import dumps as json_dumps
 except BaseException:
-    from json import dumps as json_dumps
+    from json import dumps
+
+    # This is done in order to ensure that the JSON response is
+    # kept consistent across both ujson and inbuilt json usage.
+    json_dumps = partial(dumps, separators=(",", ":"))
 
 
 class BaseHTTPResponse:
diff --git a/tests/test_response.py b/tests/test_response.py
index 7b679f43..d07eaa64 100644
--- a/tests/test_response.py
+++ b/tests/test_response.py
@@ -1,20 +1,19 @@
-import sys
 import asyncio
 import inspect
 import os
-from aiofiles import os as async_os
 from mimetypes import guess_type
+from random import choice
+from unittest.mock import MagicMock
 from urllib.parse import unquote
 
 import pytest
-from random import choice
+from aiofiles import os as async_os
 
 from sanic.response import (
     HTTPResponse, stream, StreamingHTTPResponse, file, file_stream, json
 )
 from sanic.server import HttpProtocol
 from sanic.testing import HOST, PORT
-from unittest.mock import MagicMock
 
 JSON_DATA = {'ok': True}
 
@@ -38,7 +37,6 @@ async def sample_streaming_fn(response):
 
 
 def test_method_not_allowed(app):
-
     @app.get('/')
     async def test_get(request):
         return response.json({'hello': 'world'})
@@ -55,12 +53,12 @@ def test_method_not_allowed(app):
 
     request, response = app.test_client.head('/')
     assert response.status == 405
-    assert set(response.headers['Allow'].split(', ')) == set(['GET', 'POST'])
+    assert set(response.headers['Allow'].split(', ')) == {'GET', 'POST'}
     assert response.headers['Content-Length'] == '0'
 
     request, response = app.test_client.patch('/')
     assert response.status == 405
-    assert set(response.headers['Allow'].split(', ')) == set(['GET', 'POST'])
+    assert set(response.headers['Allow'].split(', ')) == {'GET', 'POST'}
     assert response.headers['Content-Length'] == '0'
 
 
@@ -74,19 +72,62 @@ def test_response_header(app):
             'CONTENT-TYPE': 'application/json'
         })
 
-    is_windows = sys.platform in ['win32', 'cygwin']
     request, response = app.test_client.get('/')
     assert dict(response.headers) == {
         'Connection': 'keep-alive',
         'Keep-Alive': str(app.config.KEEP_ALIVE_TIMEOUT),
-        # response body contains an extra \r at the end if its windows
-        # TODO: this is the only place this difference shows up in our tests
-        # we should figure out a way to unify testing on both platforms
-        'Content-Length': '12' if is_windows else '11',
+        'Content-Length': '11',
         'Content-Type': 'application/json',
     }
 
 
+def test_response_content_length(app):
+    @app.get("/response_with_space")
+    async def response_with_space(request):
+        return json({
+            "message": "Data",
+            "details":   "Some Details"
+        }, headers={
+            'CONTENT-TYPE': 'application/json'
+        })
+
+    @app.get("/response_without_space")
+    async def response_without_space(request):
+        return json({
+            "message":"Data",
+            "details":"Some Details"
+        }, headers={
+            'CONTENT-TYPE': 'application/json'
+        })
+
+    _, response = app.test_client.get("/response_with_space")
+    content_length_for_response_with_space = response.headers.get("Content-Length")
+
+    _, response = app.test_client.get("/response_without_space")
+    content_length_for_response_without_space = response.headers.get("Content-Length")
+
+    assert content_length_for_response_with_space == content_length_for_response_without_space
+
+    assert content_length_for_response_with_space == '43'
+
+
+def test_response_content_length_with_different_data_types(app):
+    @app.get("/")
+    async def get_data_with_different_types(request):
+        # Indentation issues in the Response is intentional. Please do not fix
+        return json({
+            'bool':  True,
+            'none':  None,
+            'string':'string',
+            'number': -1},
+            headers={
+                'CONTENT-TYPE': 'application/json'
+            })
+
+    _, response = app.test_client.get("/")
+    assert response.headers.get("Content-Length") == '55'
+
+
 @pytest.fixture
 def json_app(app):